CI-966 (hydrochloride) [110283-66-4]
HY-103534
CAS Number110283-66-4
Product group Chemicals
Estimated Purity99.60
Molecular Weight509.87
Overview
- SupplierMedChem Express
- Product NameCI-966 (hydrochloride) [110283-66-4]
- Delivery Days Customer9
- CAS Number110283-66-4
- CertificationResearch Use Only
- Estimated Purity99.60
- Molecular FormulaC23H22ClF6NO3
- Molecular Weight509.87
- Scientific DescriptionCI-966 hydrochloride is a potent, selective, orally active and brain-penetrant inhibitor of the GABA transporter GAT-1, with IC50s of 0.26 microM and 1.2 microM for hGAT-1, rGAT-1, respectively. CI-966 hydrochloride shows more than 200-fold selectivity over GAT-2, GAT-3, and BGT-3. CI-966 hydrochloride exhibits anticonvulsant and neuroprotective activities[1][2][3].
- SMILESO=C(C1=CCCN(CCOC(C2=CC=C(C(F)(F)F)C=C2)C3=CC=C(C(F)(F)F)C=C3)C1)O.[H]Cl
- Storage Instruction2°C to 8°C
- UNSPSC12352200
