CIDE A antibody

GeneTex

CIDE A antibody

9

This antibody recognizes human CIDE-A (23kDA) and does not cross-react with CIDE-B.

WB: 0.5microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

CIDEA

cell death inducing DFFA like effector a

cell death activator CIDE-A; CIDE-A

Rabbit

IgG

Cell death activator CIDE-A

This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified. [provided by RefSeq, Aug 2010]

Human

-20°C or -80°C,2°C to 8°C

12352203