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Ciglitazone

HY-W011220
MedChem Express
CAS Number74772-77-3
Product group Chemicals
Estimated Purity98.89
Molecular Weight333.453
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Ciglitazone [74772-77-3]
  • Delivery Days Customer
    5
  • CAS Number
    74772-77-3
  • Certification
    Research Use Only
  • Estimated Purity
    98.89
  • Molecular Formula
    C18H23NO3S
  • Molecular Weight
    333.453
  • Scientific Description
    Ciglitazone is a potent and selective PPARgamma agonist ( EC 50 =3 microM). Ciglitazone inhibits proliferation and differentiation of th17 cells. Ciglitazone is a hypoglycemic agent orally active in the obese-hyperglycemic animal models. Ciglitazone induces apoptosis accompanied by activation of p38 MAPK and nuclear translocation of apoptosis inducing factor (AIF) in opossum kidney (OK) renal epithelial cells [1] [2] [3] [4] .
  • SMILES
    O=C(N1)SC(CC2=CC=C(OCC3(C)CCCCC3)C=C2)C1=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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