Ciglitazone

MedChem Express

Ciglitazone [74772-77-3]

5

74772-77-3

Research Use Only

98.89

C18H23NO3S

333.453

Ciglitazone is a potent and selective PPARgamma agonist ( EC 50 =3 microM). Ciglitazone inhibits proliferation and differentiation of th17 cells. Ciglitazone is a hypoglycemic agent orally active in the obese-hyperglycemic animal models. Ciglitazone induces apoptosis accompanied by activation of p38 MAPK and nuclear translocation of apoptosis inducing factor (AIF) in opossum kidney (OK) renal epithelial cells [1] [2] [3] [4] .

O=C(N1)SC(CC2=CC=C(OCC3(C)CCCCC3)C=C2)C1=O

-20°C,2°C to 8°C

12352200