Cilengitide (TFA salt)

Biorbyt

Cilengitide (TFA salt) [199807-35-7]

16

199807-35-7

Research Use Only

C29H41F3N8O9

702.6793

Cilengitide is a potent integrin inhibitor for alphavbeta3 receptor and alphavbeta5 receptor with IC50 of 4.1 nM and 79 nM, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2.

FC(C(=O)O[H])(F)F.O=C1[C@]([H])(C([H])(C([H])([H])[H])C([H])([H])[H])N(C([H])([H])[H])C([C@@]([H])(C([H])([H])C2C([H])=C([H])C([H])=C([H])C=2[H])N([H])C([C@]([H])(C([H])([H])C(=O)O[H])N([H])C(C([H])([H])N([H])C([C@]([H])(C([H])([H])C([H])([H])C([H])([H])/

12352200