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Ciliobrevin A [302803-72-1]

Ciliobrevin A [302803-72-1]

T3156
TargetMol Chemicals
CAS Number302803-72-1
Product group Chemicals
Estimated Purity97.10%
Molecular Weight358.18
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Ciliobrevin A [302803-72-1]
  • Delivery Days Customer
    4
  • CAS Number
    302803-72-1
  • Certification
    Research Use Only
  • Chemical Name
    Ciliobrevin A
  • Estimated Purity
    97.10%
  • Molecular Formula
    C17H9Cl2N3O2
  • Molecular Weight
    358.18
  • Scientific Description
    Ciliobrevin A (HPI-4) is an inhibitor of the hedgehog signaling pathway with an IC50 of less than 10 microM.
  • Shelf life instruction
    3 years
  • SMILES
    Clc1ccc(C(=O)C(\C#N)=C2\NC(=O)c3ccccc3N2)c(Cl)c1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Jung IH, Jung DE, Park YN, et al. Aberrant Hedgehog ligands induce progressive pancreatic fibrosis by paracrine activation of myofibroblasts and ductular cells in transgenic zebrafish. PLoS One. 2011,6(12):e27941. doi: 10.1371/journal.pone.0027941
    Read this paper