Ciliobrevin D

MedChem Express

Ciliobrevin D [1370554-01-0]

10

1370554-01-0

Research Use Only

99.36

C17H8Cl3N3O2

392.62

Ciliobrevin D is a cell-permeable, reversible and specific inhibitor of AAA+ ATPase motor cytoplasmic dynein . Ciliobrevin D inhibits Hedgehog (Hh) signaling and primary cilia formation. Ciliobrevin D inhibits dynein -dependent microtubule gliding and ATPase activity in vitro [1] [2] .

O=C(C1=C(C=C(Cl)C=C1)Cl)/C(C#N)=C(N2)/NC3=CC(Cl)=CC=C3C2=O

-20°C,2°C to 8°C

12352200