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Ciliobrevin D [1370554-01-0]

Ciliobrevin D [1370554-01-0]

T14965
TargetMol Chemicals
CAS Number1370554-01-0
Product group Chemicals
Estimated Purity98.09%
Molecular Weight392.62
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Ciliobrevin D
  • Delivery Days Customer
    4
  • CAS Number
    1370554-01-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Ciliobrevin D
  • Estimated Purity
    98.09%
  • Molecular Formula
    C17H8Cl3N3O2
  • Molecular Weight
    392.62
  • Scientific Description
    Ciliobrevin D is a AAA+ ATPase motor cytoplasmic dynein inhibitor. Ciliobrevin D inhibits Hedgehog (Hh) signaling and primary cilia formation and it also inhibits dynein-dependent microtubule gliding and ATPase activity in vitro.
  • Shelf life instruction
    3 years
  • SMILES
    Clc1ccc(C(=O)C(\C#N)=C2/NC(=O)c3ccc(Cl)cc3N2)c(Cl)c1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Dynein 1 supports spermatid transport and spermiation during spermatogenesis in the rat testis. Wen Q et al., 2018 Nov 1, Am J Physiol Endocrinol Metab
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