Cilomilast
HY-10790
Overview
- SupplierMedChem Express
- Product NameCilomilast [153259-65-5]
- Delivery Days Customer10
- CAS Number153259-65-5
- CertificationResearch Use Only
- Estimated Purity99.91
- Molecular FormulaC20H25NO4
- Molecular Weight343.42
- Scientific DescriptionCilomilast (SB-207499) is a potent, selective and orally active inhibitor of Phosphodiesterase 4 (PDE4) , with IC 50 s of ~100 and 120 nM for LPDE4 and HPDE4, respectively. Cilomilast shows selectivity for PDE4 over PDE1, PDE2, PDE3 and PDE5 ( IC 50 =74, 65, >100, and 83 microM, respectively). Cilomilast has anti-inflammatory and immunomodulatory effects and can be used for thr research of asthma and chronic obstructive pulmonary disease (COPD) [1] [2] [3] .
- SMILESO=C([C@H]1CC[C@@](C#N)(CC1)C2=CC=C(OC)C(OC3CCCC3)=C2)O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
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Product group Chemicals
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Molecular Weight343.4 Da
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![Cilomilast [153259-65-5]](https://www.targetmol.com/group3/M00/37/E9/CgoaEWayU8SEYoXIAAAAAA9xp8s956.png)
Product group Chemicals
CAS Number153259-65-5
Estimated Purity98%
Molecular Weight343.42
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