Cinrebafusp alfa [2218515-90-1]
HY-P99605
Product group Antibodies
Overview
- SupplierMedChem Express
- Product NameCinrebafusp alfa [2218515-90-1]
- Delivery Days Customer10
- CAS Number2218515-90-1
- CertificationResearch Use Only
- Estimated Purity98.53
- Scientific DescriptionCinrebafusp alfa (PRS 343) is a high affinity CD137/HER2 bispecfic anticalin-based drug. Cinrebafusp alfa binds to recombinant human HER2 (Kd=0.3 nM) and human monomeric CD137 (4-1BB; Kd=5 nM). Cinrebafusp alfa facilitates T-cell costimulation by tumor-localized, HER2-dependent 4-1BB clustering and activation, further enhancing T-cell receptor-mediated activity and leading to tumor destruction. Cinrebafusp alfa has the potential for HER2+ solid tumors research[1][2].
- Storage Instruction-80°C
- UNSPSC41116161