Cipralisant [213027-19-1]

MedChem Express

Cipralisant [213027-19-1]

10

213027-19-1

Research Use Only

99.26

C14H20N2

216.32

Cipralisant (GT-2331) is an orally active, low-toxicity, potent, selective, high affinity histamine H3 receptor full antagonist in vivo, and an agonist in vitro, with a pKi of 9.9 for histamine H3 receptor and a Ki of 0.47 nM for rat histamine H3 receptor. Cipralisant has the potential for attention-deficit hyperactivity disorder research[1][2][3][4]. Cipralisant is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

CC(C)(C)CCC#C[C@H]1[C@H](C2=CN=CN2)C1

-20°C,2°C to 8°C

12352200