CITCO [338404-52-7]

MedChem Express

CITCO [338404-52-7]

10

338404-52-7

Research Use Only

99.60

C19H12Cl3N3OS

436.74

CITCO, an imidazothiazole derivative, is a selective Constitutive androstane receptor (CAR) agonist. CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR), and no activity on other nuclear receptors[1].

ClC1=CC=C(C2=C(/C=N/OCC3=CC=C(Cl)C(Cl)=C3)N4C(SC=C4)=N2)C=C1

-20°C

12352200