CJ-42794 [847728-01-2]

TargetMol Chemicals

CJ-42794 [847728-01-2]

4

847728-01-2

Chemical

Research Use Only

CJ-42794

C22H17ClFNO4

413.83

CJ-42794 (CJ-042794) is a selective antagonist of the prostaglandin E receptor subtype 4 (EP4), inhibiting [3H]-PGE2 binding to the human EP4 receptor with a mean pKi of 8.5. It exhibits a binding affinity that is at least 200-fold more selective for the human EP4 receptor than for other human EP receptor subtypes (EP1, EP2, and EP3) (IC50: 8.5 (pKi)).

3 years

C[C@H](NC(=O)c1cc(Cl)ccc1Oc1ccc(F)cc1)c1ccc(cc1)C(O)=O

-20°C

12352200