CK-2-68

MedChem Express

CK-2-68 [1361004-87-6]

5

1361004-87-6

Research Use Only

C24H17ClF3NO2

443.85

CK-2-68 is an inhibitor for complex III in protozoan mitochondrial respiratory chain, by targeting the alternative NADH dehydrogenase ( NDH2 ) of the malarial parasite Plasmodium . CK-2-68 exhibits antimalaria efficacy, that inhibits Plasmodium falciparum infected erythrocytes with an IC 50 of 40 nM [1] .

O=C1C(C)=C(NC2=C1C=CC(Cl)=C2)C3=CC=C(C=C3)CC4=CC=C(C=C4)OC(F)(F)F

12352200