CK-666

MedChem Express

CK-666 [442633-00-3]

10

442633-00-3

Research Use Only

99.17

C18H17FN2O

296.34

CK-666 is a cell-permeable actin-related protein Arp2/3 complex inhibitor ( IC 50 =12 microM). CK-666 binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocking movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation [1] [2] .

O=C(NCCC1=C(C)NC2=C1C=CC=C2)C3=CC=CC=C3F

-20°C,2°C to 8°C

12352200