CL2 Linker [2270986-66-6]
HY-128947
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product NameCL2 Linker [2270986-66-6]
- Delivery Days Customer10
- CAS Number2270986-66-6
- CertificationResearch Use Only
- Molecular FormulaC68H103N11O22
- Molecular Weight1426.61
- Scientific DescriptionCL2 Linker is a cleavableADC linker. CL2-SN-38 and CL2A-SN-38 are equivalent in agent substitution (~6), cell binding (Kd ~1.2 nM), cytotoxicity (IC50 ~2.2 nM), and serum stability in vitro (t1/2 ~20 hours)[1][2].
- SMILESOCC(COC(N(C)CCN(C)C(OCC(C=C1)=CC=C1NC([C@H](CCCCNC(OC(C)(C)C)=O)NC([C@@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOCCN2C=C(CNC(CCCCCN3C(C=CC3=O)=O)=O)N=N2)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O
- UNSPSC41115800