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ProductsBack/CL2A-SN38 [1279680-68-0]
Chemical Structure
Chemical Structure
Chemical Structure

CL2A-SN38 [1279680-68-0]

Research Use Only
82256
BPS Bioscience
CAS Number1279680-68-0
Product group Chemicals
Molecular Weight1480.6 Da
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Overview

  • Supplier
    BPS Bioscience
  • Product Name
    CL2A-SN38
  • Delivery Days Customer
    7
  • CAS Number
    1279680-68-0
  • Certification
    Research Use Only
  • Molecular Formula
    C73H97N11O22
  • Molecular Weight
    1480.6 Da
  • Scientific Description
    CL2A-SN38 is a SN38 derivative with a Mal-PEG attached peptide linker, it can easily react with antibody to form an antibody-drug conjugate (ADC). SN-38 is a potent DNA Topoisomerase I inhibitor. CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A linker is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200