clasto-Lactacystin beta-lactone [154226-60-5]

AdipoGen Life Sciences

clasto-Lactacystin beta-lactone

10

154226-60-5

Research Use Only

>95%

C10H15NO4

213.2

Chemical. CAS: 154226-60-5. Formula: C10H15NO4. MW: 213.2. Potent and selective irreversible and cell permeable proteasome inhibitor. Inhibits the chymotrypsin-like, trypsin-like and caspase-like peptidase activity of the proteasome. The active metabolite of lactacystin (Prod. No. AG-CN2-0104) with higher potency since it does not require hydrolysis in order to become cell permeable. Calpain and cathepsin inhibitor. Apoptosis inducer. Anticancer compound. Induces differentiation and inhibits cell cycle progression in several tumor cell lines. Induces neuritogenesis. Autophagy inducer. - Potent and selective irreversible and cell permeable proteasome inhibitor. Inhibits the chymotrypsin-like, trypsin-like and caspase-like peptidase activity of the proteasome. The active metabolite of lactacystin (Prod. No. AG-CN2-0104) with higher potency since it does not require hydrolysis in order to become cell permeable. Calpain and cathepsin inhibitor. Apoptosis inducer. Anticancer compound. Induces differentiation and inhibits cell cycle progression in several tumor cell lines. Induces neuritogenesis. Autophagy inducer.

CC(C)[C@H](O)C12NC(=O)[C@H](C)[C@@H]1OC2=O

-20°C,2°C to 8°C

12352200