Western Blot analysis of 3T3 cells using Cleaved-CASP4 p20 (Q81) Polyclonal Antibody at dilution of 1:2000.
Western Blot analysis of 3T3 cells using Cleaved-CASP4 p20 (Q81) Polyclonal Antibody at dilution of 1:2000.
Cleaved-Caspase-4 p20 (Q81) Polyclonal Antibody
E-AB-30021
Protein IDP49662
Product group Proteins / Signaling Molecules
Overview
- SupplierElabscience
- Product NameCleaved-Caspase-4 p20 (Q81) Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierWB,IHC,ELISA
- CertificationResearch Use Only
- Concentration1 mg/ml
- Protein IDP49662
- Protein NameCaspase-4
- Scientific DescriptionThis gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is caspase 4, apoptosis-related cysteine peptidase, this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9.
- UNSPSC12352202