
IHC image of CSB-PA891553LA01HU diluted at 1:600 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
CLEC4E Antibody
CSB-PA891553LA01HU
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCLEC4E
Overview
- SupplierCusabio
- Product NameCLEC4E Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID26253
- Target nameCLEC4E
- Target descriptionC-type lectin domain family 4 member E
- Target synonymsCLECSF9, MINCLE, C-type lectin domain family 4 member E, C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 9, C-type lectin superfamily member 9, macrophage-inducible C-type lectin
- HostRabbit
- IsotypeIgG
- Protein IDQ9ULY5
- Protein NameC-type lectin domain family 4 member E
- Scientific DescriptionC-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161






