Clemizole [442-52-4]

MedChem Express

Clemizole [442-52-4]

10

442-52-4

Research Use Only

C19H20ClN3

325.84

Clemizole is an H1 histamine receptor antagonist, is found to substantially inhibit HCV replication. Clemizole is an inhibitor of TRPC5 channel. The IC50 of Clemizole for RNA binding by NS4B is 24+/-1 nM, whereas its EC50 for viral replication is 8 microM.

ClC1=CC=C(C=C1)CN2C(CN3CCCC3)=NC4=CC=CC=C24

12352200