Clindamycin Sulfoxide

MedChem Express

Clindamycin Sulfoxide [22431-46-5]

5

22431-46-5

Research Use Only

C18H33ClN2O6S

440.98

Clindamycin sulfoxide is an active metabolite of the antibiotic Clindamycin (HY-B1455). It is formed via S-oxidation of clindamycin primarily by the cytochrome P450 (CYP) isoform CYP3A4. Clindamycin sulfoxide inhibits the growth of P. prevotti, B. fragilis, and C. sordelli in vitro with MIC values of 2, 2, and 1 mg/L, respectively.

O=C([C@H]1N(C[C@@H](C1)CCC)C)N[C@@]([H])([C@]2(O[C@@]([H])([C@@H]([C@H]([C@H]2O)O)O)S(C)=O)[H])[C@@H](Cl)C

12352200