Clobenpropit (dihydrobromide)

MedChem Express

Clobenpropit (dihydrobromide) [145231-35-2]

10

145231-35-2

98.99

C14H19Br2ClN4S

470.65

Clobenpropit dihydrobromide is a potent histamine H3R antagonist/inverse agonist with a pEC 50 of 8.07 for histamine H3LR [1] . Clobenpropit dihydrobromide acts as partial agonist at histamine H4 receptors ( K i 13 nM). Clobenpropit dihydrobromide also binds to serotonin 5-HT3 receptors (K i 7.4 nM) and alpha2A/alpha2C adrenoceptors (K i 17.4/7.8 nM) [2] . Clobenpropit dihydrobromide increases apoptosis [3] .

N=C(SCCCC1=CN=CN1)NCC2=CC=C(Cl)C=C2.[H]Br.[H]Br

2°C to 8°C

12352200