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Closantel (sodium) [61438-64-0]

Research Use Only
HY-17596A
MedChem Express
CAS Number61438-64-0
Product group Chemicals
Estimated Purity99.76
Molecular Weight685.06
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Closantel (sodium) [61438-64-0]
  • Delivery Days Customer
    9
  • CAS Number
    61438-64-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.76
  • Molecular Formula
    C22H13Cl2I2N2NaO2
  • Molecular Weight
    685.06
  • Scientific Description
    Closantel sodium is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel sodium is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 microM and a Ki of 468 nM. Closantel sodium inhibits the O. volvulus L3 to L4 molt of developing[1][2].
  • SMILES
    O=C(NC1=CC(Cl)=C(C(C2=CC=C(Cl)C=C2)C#N)C=C1C)C3=CC(I)=CC(I)=C3O[Na]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200