Clozapine N-oxide (dihydrochloride) [2250025-93-3]
HY-17366A
CAS Number2250025-93-3
Product group Chemicals
Estimated Purity99.74
Molecular Weight415.74
Overview
- SupplierMedChem Express
- Product NameClozapine N-oxide (dihydrochloride) [2250025-93-3]
- Delivery Days Customer10
- CAS Number2250025-93-3
- CertificationResearch Use Only
- Estimated Purity99.74
- Molecular FormulaC18H21Cl3N4O
- Molecular Weight415.74
- Scientific DescriptionClozapine N-oxide dihydrochloride is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide dihydrochloride activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide dihydrochloride cannot cross the blood-brain barrier[1][2][3][4]. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor (EC50=11 nM) agonist[5][6].
- SMILESC[N+]1([O-])CCN(C2=NC3=CC(Cl)=CC=C3NC4=CC=CC=C42)CC1.[H]Cl.[H]Cl
- Storage Instruction2°C to 8°C
- UNSPSC12352200