CLPS Polyclonal Antibody
RD75715A
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCLPS
Overview
- SupplierReddot Biotech
- Product NameCLPS Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.6 mg/ml
- ConjugateUnconjugated
- Gene ID1208
- Target nameCLPS
- Target descriptioncolipase
- Target synonymscolipase; colipase, pancreatic; pancreatic colipase preproprotein
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203