CM-579 [1846570-40-8]

MedChem Express

CM-579 [1846570-40-8]

10

1846570-40-8

Research Use Only

C29H40N4O3

492.65

CM-579 is a first-in-class reversible, dual inhibitor of G9a and DNMT, with IC50 values of 16 nM, 32 nM for G9a and DNMT, respectively. Has potent in vitro cellular activity in a wide range of cancer cells[1].

CN1CCC(CNC2=CC(C3=CC=C(C)O3)=NC4=CC(OCCCN5CCCC5)=C(OC)C=C24)CC1

12352200