CM037

MedChem Express

CM037 [896795-60-1]

10

896795-60-1

Research Use Only

99.55

C21H25N3O3S2

431.57

CM037 is a highly selective and competitive ALDH1A1 inhibitor (IC50=4.6 microM). CM037 blocks the catalytic activity of ALDH1A1, thereby inhibiting the activation of the downstream HIF-1alpha/VEGF pathway. CM037 is mainly used to study the ALDH1A1-mediated regulation of cancer stem cells (CSCs) and angiogenesis, especially in breast cancer, showing the potential to inhibit tumor angiogenesis and stem cell characteristics[1][2].

O=C1C2=C(N=C(SCC(OCC)=O)N1CCCN3CCCC3)C4=CC=CC=C4S2

-20°C,2°C to 8°C

12352200