CMC2.24 [1255639-43-0]
HY-120793
CAS Number1255639-43-0
Product group Chemicals
Estimated Purity97.48
Molecular Weight427.45
Overview
- SupplierMedChem Express
- Product NameCMC2.24 [1255639-43-0]
- Delivery Days Customer10
- CAS Number1255639-43-0
- CertificationResearch Use Only
- Estimated Purity97.48
- Molecular FormulaC26H21NO5
- Molecular Weight427.45
- Scientific DescriptionCMC2.24 (TRB-N0224), an orally active tricarbonylmethane agent, is effective against pancreatic tumor in mice by inhibiting Ras activation and its downstream effector ERK1/2 pathway. CMC2.24 is also a potent inhibitor of zinc-dependent MMPs with IC50s ranging from 2.0-69 microM. CMC2.24 alleviates osteoarthritis progression by restoring cartilage homeostasis and inhibiting chondrocyte apoptosis via the NF-kappaB/HIF-2alpha axis[1][2][3].
- SMILESO=C(NC1=CC=CC=C1)C(C(/C=C/C2=CC=C(O)C=C2)=O)C(/C=C/C3=CC=C(O)C=C3)=O
- Storage Instruction-20°C
- UNSPSC12352200
MSDS
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Product group Chemicals
CMC2.24 [1255639-43-0]T36492
CAS Number1255639-43-0
Molecular Weight427.45
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Product group Chemicals
CMC2.24ORB1693685
CAS Number1255639-43-0
Estimated Purity98.00%
Molecular Weight427.45
- SizePrice