(-)-CMLD010509
HY-119271A
Molecular Weight556.40
Product group Chemicals
Overview
- SupplierMedChem Express
- Product Name(-)-CMLD010509
- Delivery Days Customer5
- CertificationResearch Use Only
- Molecular FormulaC27H26BrNO7
- Molecular Weight556.40
- Scientific Description(-)-CMLD010509 ((-)-SDS-1-021) is an isomer of CMLD010509 (SDS-1-021) (HY-119271). CMLD010509 (SDS-1-021) is a highly specific inhibitor of the oncogenic translation program supporting multiple myeloma (MM)-including key oncoproteins such as MYC, MDM2, CCND1, MAF, and MCL-1. CMLD010509 (SDS-1-021) shows an IC50 below 10 nM for most MM cell lines and induces apoptosis. CMLD010509 (SDS-1-021) is a potent and selective translation inhibitor through an eIF4E phosphorylation-independent mechanism[1].
- SMILESO[C@]12[C@](OC3=CC(OC)=CC(OC)=C32)(C4=CC=C(C=C4)Br)[C@H](C5=CC=CC=C5)[C@H]([C@H]1O)C(NOC)=O
- UNSPSC12352200