
Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA871398ESR2HU at dilution of 1:100
CNOT8 Antibody
CSB-PA871398ESR2HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCNOT8
Overview
- SupplierCusabio
- Product NameCNOT8 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID9337
- Target nameCNOT8
- Target descriptionCCR4-NOT transcription complex subunit 8
- Target synonymsCAF1; Caf1b; CAF1-like protein; CAF2; CALIF; CALIFp; CCR4-associated factor 8; CCR4-NOT transcription complex subunit 8; hCAF1; PGK promoter directed over production; POP2
- HostRabbit
- IsotypeIgG
- Protein IDQ9UFF9
- Protein NameCCR4-NOT transcription complex subunit 8
- Scientific DescriptionHas 3-5 poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161