Cobicistat

MedChem Express

Cobicistat [1004316-88-4]

10

1004316-88-4

Research Use Only

99.77

C40H53N7O5S2

776.02

Cobicistat is a potent and selective inhibitor of cytochrome P450 3A (CYP3A) enzymes with IC 50 s of 30-285 nM. Cobicistat is a pharmacokinetic enhancer?which increases the overall absorption of several HIV medications.

CN(C(N[C@@H](CCN1CCOCC1)C(N[C@@H](CC2=CC=CC=C2)CC[C@@H](NC(OCC3=CN=CS3)=O)CC4=CC=CC=C4)=O)=O)CC5=CSC(C(C)C)=N5

-20°C,2°C to 8°C

12352200