Coclaurine [486-39-5]
HY-N3610
CAS Number486-39-5
Product group Chemicals
Estimated Purity98.97
Molecular Weight285.34
Overview
- SupplierMedChem Express
- Product NameCoclaurine [486-39-5]
- Delivery Days Customer5
- CAS Number486-39-5
- CertificationResearch Use Only
- Estimated Purity98.97
- Molecular FormulaC17H19NO3
- Molecular Weight285.34
- Scientific DescriptionCoclaurine is a class of tetrahydroisoquinoline alkaloids that can be isolated from Sarcopetalum harveyanum with anticancer activity. Coclaurine is a nicotinic acetylcholine receptor (nAChRs) antagonist. Coclaurine is a key molecule in S. tetrandra responsible for EFHD2 inhibition. Coclaurine can downregulate EFHD2-related NOX4-ABCC1 signaling and enhanced Cisplatin (HY-17394) sensitivity. Coclaurine suppresses the stemness and metastatic properties of NSCLC cells. Coclaurine disrupts the interaction between the transcription factor FOXG1 and the EFHD2 promoter, leading to a reduction in EFHD2 transcription[1][2][3][4].
- SMILESOC1=CC2=C(C=C1OC)CCN[C@H]2CC3=CC=C(O)C=C3
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
MSDS
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Product group Chemicals
Coclaurine [486-39-5]AAA48639
CAS Number486-39-5
Molecular Weight285.34 g/mol
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![(S)-Coclaurine [486-39-5]](https://www.targetmol.com/group3/M00/02/F8/CgoaEGY7QxaEBwFFAAAAAPPxm_4532.png)
Product group Chemicals
CAS Number486-39-5
Molecular Weight285.34
- SizePrice
