Coelonin [82344-82-9]

MedChem Express

Coelonin [82344-82-9]

10

82344-82-9

Research Use Only

98.0

C15H14O3

242.27

Coelonin is a dihydrophenanthrene with anti-inflammation activity. Coelonin inhibits LPS-induced PTEN phosphorylation. Coelonin inhibits NF-kappaB activation and p27Kip1 degradation by regulating the PI3K/AKT pathway negatively. Coelonin can inhibit IkappaBalpha phosphorylation and degradation and increases the expression of IkappaBalpha protein[1][2].

OC(C=C1CC2)=CC(OC)=C1C3=C2C=C(O)C=C3

-20°C

12352200