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Cofetuzumab Pelidotin

82930
BPS Bioscience
TargetPTK7
Product group Antibodies
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Overview

  • Supplier
    BPS Bioscience
  • Product Name
    Cofetuzumab Pelidotin
  • Delivery Days Customer
    23
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Estimated Purity
    ≥90%
  • Gene ID5754
  • Target name
    PTK7
  • Target description
    protein tyrosine kinase 7 (inactive)
  • Target synonyms
    CCK4; CCK-4; colon carcinoma kinase 4; inactive tyrosine-protein kinase 7; pseudo tyrosine kinase receptor 7; PTK7 protein tyrosine kinase 7; tyrosine-protein kinase-like 7
  • Protein IDQ13308
  • Protein Name
    Inactive tyrosine-protein kinase 7
  • Scientific Description
    Cofetuzumab pelidotin (PF-06647020) is a PTK7-targeting ADC comprising a humanized anti-PTK7 mAb (hu6M024, IgG1) joined to an auristatin microtubule inhibitor payload, auristatin-0101 (Aur0101), by a cleavable valine-citrulline (vc)-based linker. Cofetuzumab pelidotin has a DAR of 4. Cofetuzumab pelidotin binds to cell-surface PTK7 with an EC50 of 1153 pM by flow cytometry. Cofetuzumab pelidotin has the potential for solid tumors research1,2,3.
  • Storage Instruction
    -80°C
  • UNSPSC
    12352203

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