COH000

MedChem Express

COH000 [1534358-79-6]

10

1534358-79-6

Research Use Only

98.0

C25H25NO5

419.47

COH000 is an allosteric, covalent and irreversible inhibitor of ubiquitin-like 1-activating enzyme (SUMO-activating enzyme) (E1) , with an IC 50 of 0.2 microM for SUMOylation in vitro [1] .

CC(C=C1)=CC=C1C[C@@H](NC2=CC=CC=C2)[C@]34C(C(OC)=O)=C(C(OC)=O)[C@@H](O4)C=C3

-20°C,2°C to 8°C

12352200