Col003

MedChem Express

Col003 [328565-16-8]

10

328565-16-8

Research Use Only

99.87

C14H11NO4

257.24

Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen binding site on Hsp47 ( IC 50 =1.8 microM). Col003 discourages the interaction of Hsp47 with collagen and inhibits collagen secretion by destabilizing the collagen triple helix. Col003 can be used for the investigation of fibrosis [1]

O=CC1=CC(CC2=CC=CC=C2)=CC([N+]([O-])=O)=C1O

2°C to 8°C

12352200