ICC/IF analysis of formalin-fixed K562 cells using GTX55142 COL11A1 antibody. Red : Primary antibody Blue : DAPI Permeabilization : 0.1% Triton X-100 in TBS for 5-10 minutes
ICC/IF analysis of formalin-fixed K562 cells using GTX55142 COL11A1 antibody. Red : Primary antibody Blue : DAPI Permeabilization : 0.1% Triton X-100 in TBS for 5-10 minutes
COL11A1 antibody
GTX55142
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetCOL11A1
Overview
- SupplierGeneTex
- Product NameCOL11A1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:1000. ICC/IF: 1:100 - 1:500. IHC-P: 1:100 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1301
- Target nameCOL11A1
- Target descriptioncollagen type XI alpha 1 chain
- Target synonymsCO11A1, COLL6, DFNA37, STL2, collagen alpha-1(XI) chain, collagen XI, alpha-1 polypeptide, collagen, type XI, alpha 1, deafness, autosomal dominant 37
- HostRabbit
- IsotypeIgG
- Protein IDP12107
- Protein NameCollagen alpha-1(XI) chain
- Scientific DescriptionThis gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single-nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Wu YH, Huang YF, Wu PY, et al. The downregulation of miR-509-3p expression by collagen type XI alpha 1-regulated hypermethylation facilitates cancer progression and chemoresistance via the DNA methyltransferase 1/Small ubiquitin-like modifier-3 axis in ovarian cancer cells. J Ovarian Res. 2023,16(1):124. doi: 10.1186/s13048-023-01191-5Read this paper
- Wu YH, Huang YF, Wu PY, et al. The Downregulation of miR-509-3p Expression by Collagen Type XI Alpha 1-Regulated Hypermethylation Facilitates Cancer Progression and Chemoresistance via the DNA Methyltransferase 1/Small Ubiquitin-like Modifier-3 Axis in Ovarian Cancer Cells. Res Sq. 2023,:pii: rs.3.rs-2592453. doi: 10.21203/rs.3.rs-2592453/v1.Read this paper
- Wu YH, Huang YF, Chang TH, et al. miR-335 Restrains the Aggressive Phenotypes of Ovarian Cancer Cells by Inhibiting COL11A1. Cancers (Basel). 2021,13(24). doi: 10.3390/cancers13246257Read this paper
- Wu YH, Huang YF, Chen CC, et al. Comparing PI3K/Akt Inhibitors Used in Ovarian Cancer Treatment. Front Pharmacol. 2020,11:206. doi: 10.3389/fphar.2020.00206Read this paper
- Wu YH, Huang YF, Chen CC, et al. Akt inhibitor SC66 promotes cell sensitivity to cisplatin in chemoresistant ovarian cancer cells through inhibition of COL11A1 expression. Cell Death Dis. 2019,10(4):322. doi: 10.1038/s41419-019-1555-8Read this paper
- Wu YH, Huang YF, Chang TH, et al. Activation of TWIST1 by COL11A1 promotes chemoresistance and inhibits apoptosis in ovarian cancer cells by modulating NF-κB-mediated IKKβ expression. Int J Cancer. 2017,141(11):2305-2317. doi: 10.1002/ijc.30932Read this paper
Datasheet
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