COL11A2 antibody [GT6410]
![Research Use Only](static/images/certificates/ruo.jpg)
GTX629739
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCOL11A2
Overview
- SupplierGeneTex
- Product NameCOL11A2 antibody [GT6410]
- Delivery Days Customer9
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGT6410
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1302
- Target nameCOL11A2
- Target descriptioncollagen type XI alpha 2 chain
- Target synonymscollagen alpha-2(XI) chain; collagen, type XI, alpha 2; DFNA13; DFNB53; FBCG2; HKE5; OSMEDA; OSMEDB; PARP; pro-a2 chain of collagen type XI; STL3
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThis gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Three transcript variants encoding different isoforms have been identified for this gene. A pseudogene is located nearby on chromosome 6. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203