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Chemical Structure
Chemical Structure
Chemical Structure

Colcemid

AG-CR1-3567
AdipoGen Life Sciences
CAS Number477-30-5
Product group Chemicals
Estimated Purity>98%
Molecular Weight371.4
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Colcemid
  • Delivery Days Customer
    10
  • CAS Number
    477-30-5
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Hazard Information
    Danger,Excepted quantity
  • Molecular Formula
    C21H25NO5
  • Molecular Weight
    371.4
  • Scientific Description
    Anti-cancer compound [2, 6, 7, 10, 11, 14]. Cell synchronization agent. Used as a drug in chemotherapy by synchronizing tumor cells at metaphase, the radiosensitive stage of the cell cycle [11, 12, 14]. Microtubule assembly inhibitor. Depolymerizes microtubules and limits microtubule formation (inactivates spindle fibre formation) [1, 4, 5, 14]. Inhibits mitosis during cell division at metaphase by inhibiting spindle formation [2, 5, 7, 8, 14]. Low concentrations affect microtubule dynamics and cell migration, while high concentrations promote microtubule detachment from microtubule organizing center [14]. Apoptosis inducer [9, 13]. Thrombopoietic agent [3]. - Chemical. CAS: 477-30-5. Formula: C21H25NO5. MW: 371.4. Semisynthetic from colchicine (Prod. No. AG-CN2-0048). Anti-cancer compound. Cell synchronization agent. Used as a drug in chemotherapy by synchronizing tumor cells at metaphase, the radiosensitive stage of the cell cycle. Microtubule assembly inhibitor. Depolymerizes microtubules and limits microtubule formation (inactivates spindle fibre formation). Inhibits mitosis during cell division at metaphase by inhibiting spindle formation. Low concentrations affect microtubule dynamics and cell migration, while high concentrations promote microtubule detachment from microtubule organizing center. Apoptosis inducer. Thrombopoietic agent.
  • SMILES
    CNC1CCC2=C(C(OC)=C(OC)C(OC)=C2)C2=CC=C(OC)C(=O)C=C12
  • Storage Instruction
    -20°C,2°C to 8°C
  • UN Number
    UN 2811
  • UNSPSC
    12352200

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Chemodex
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