Combretastatin A-1 [109971-63-3]

MedChem Express

Combretastatin A-1 [109971-63-3]

10

109971-63-3

Research Use Only

97.03

C18H20O6

332.35

Combretastatin A-1 is a microtubule polymerization inhibitor that binds to the colchicine-binding site of tubulin. Combretastatin A-1 inhibits the Wnt/beta-catenin pathway through tubulin depolymerization mediated AKT deactivation. Combretastatin A-1 exhibits anti-tumor and anti-vascular effects[1][2][3].

COC1=CC=C(/C=C\C2=CC(OC)=C(C(OC)=C2)OC)C(O)=C1O

-20°C,2°C to 8°C

12352200