Complete ADP-Ribosylation Cycle Inhibitor Cocktail

BPS Bioscience

Complete ADP-Ribosylation Cycle Inhibitor Cocktail

7

1207456-01-6

Research Use Only

Olaparib: C24H23FN4O3 Talazoparib: C19H14F2N6O XAV-939: C14H11F3N2OS RBN-2397: C20H23F6N7O3 RBN-012759: C19H23FN2O3S PDD00017273: C23H26N6O4S2

Olaparib: 434.5; Talazoparib: 380.4; XAV-939: 312.31; RBN-2397: 523.43; RBN-012759: 378.5; PDD00017273: 514.62

The Complete ADP-Ribosylation Cycle Inhibitor Cocktail is a mixture of selected highly selective ADP-ribosylation cycle inhibitors and broad specificity inhibitors. This product contains five ADP-ribosylation cycle inhibitors of Poly (ADP-ribose) polymerase (PARP) isozymes such as Olaparib, Talazoparib, XAV-939, RBN-2397, RBN-012759, and one potent, selective poly (ADP-ribose) glycohydrolase/PARG inhibitor, PDD00017273. Used all together, these inhibitors freeze the state of cellular ribosylation at the time the mix is applied to the cells. This product is designed to supplement a cell lysis buffer of choice to prevent post-lysis changes in the ADP-ribosylation status of extracted proteins.

-80°C

12352200