Compound E [209986-17-4]
HY-14176
CAS Number209986-17-4
Product group Chemicals
Estimated Purity99.97
Molecular Weight490.50
Overview
- SupplierMedChem Express
- Product NameCompound E [209986-17-4]
- Delivery Days Customer5
- CAS Number209986-17-4
- CertificationResearch Use Only
- Estimated Purity99.97
- Molecular FormulaC27H24F2N4O3
- Molecular Weight490.50
- Scientific DescriptionCompound E is a gamma-secretase inhibitor. Compound E blocks beta-amyloid(40), beta-amyloid(42), and Notch gamma-secretase cleavage with IC50s of 0.24, 0.37, 0.32 nM, respectively.
- SMILESFC1=CC(CC(N[C@@H](C)C(N[C@@H]2C(N(C)C(C=CC=C3)=C3C(C4=CC=CC=C4)=N2)=O)=O)=O)=CC(F)=C1
- Storage Instruction-20°C
- UNSPSC12352200

![gamma-Secretase-IN-1 [209986-17-4]](https://www.targetmol.com/group3/M00/36/8A/CgoaEGayQCOEB-SEAAAAAGcqvCU051.png)