ELISA detection of COMT using GTX101233 for capture at a concentration of 2.5 microg/mL and GTX89277 for detection at a concentration of 0.5 microg/mL. The HRP-conjugated anti-goat IgG antibody (GTX26741) was diluted at 1:20,000-1:200,000 and used to detect the primary antibody.
COMT ELISA Pair - COMT antibody Pair
GTX500009
Overview
- SupplierGeneTex
- Product NameCOMT ELISA Pair - COMT antibody Pair
- Delivery Days Customer9
- ApplicationsELISA
- CertificationResearch Use Only
- Gene ID1312
- Target nameCOMT
- Target descriptioncatechol-O-methyltransferase
- Target synonymscatechol O-methyltransferase; epididymis secretory sperm binding protein Li 98n; HEL-S-98n; testicular tissue protein Li 42
- Scientific DescriptionCatechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203