Copanlisib
HY-15346
CAS Number1032568-63-0
Product group Chemicals
Estimated Purity99.50
Molecular Weight480.52
Overview
- SupplierMedChem Express
- Product NameCopanlisib [1032568-63-0]
- Delivery Days Customer10
- CAS Number1032568-63-0
- CertificationResearch Use Only
- Estimated Purity99.50
- Molecular FormulaC23H28N8O4
- Molecular Weight480.52
- Scientific DescriptionCopanlisib (BAY 80-6946) is a potent, selective and ATP-competitive pan-class I PI3K inhibitor, with IC 50 s of 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kalpha , PI3Kdelta , PI3Kbeta and PI3Kgamma , respectively. Copanlisib has more than 2,000-fold selectivity against other lipid and protein kinases, except for mTOR. Copanlisib has superior antitumor activity [1] .
- SMILESO=C(C1=CN=C(N)N=C1)NC2=NC3=C(OC)C(OCCCN4CCOCC4)=CC=C3C5=NCCN25
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200