COPG antibody [N3C2], Internal
GTX105331
Overview
- SupplierGeneTex
- Product NameCOPG antibody [N3C2], Internal
- Delivery Days Customer9
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.42 mg/ml
- ConjugateUnconjugated
- Gene ID22820
- Target nameCOPG1
- Target descriptionCOPI coat complex subunit gamma 1
- Target synonymscoat protein gamma-cop; coatomer protein complex subunit gamma 1; coatomer protein complex, subunit gamma; coatomer subunit gamma; coatomer subunit gamma-1; COPG; gamma-1-coat protein; gamma-1-COP; gamma-coat protein; gamma-COP
- HostRabbit
- IsotypeIgG
- Protein IDQ9Y678
- Protein NameCoatomer subunit gamma-1
- Scientific DescriptionThe coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- RNAi screen of Salmonella invasion shows role of COPI in membrane targeting of cholesterol and Cdc42. Misselwitz B et al., 2011 Mar 15, Mol Syst BiolRead more