Western blot All lanes: COPS4 antibody at 8ug/ml Lane 1: Hela whole cell lysate Lane 2: HepG2 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 47, 41 kDa Observed band size: 47 kDa

COPS4 Antibody

Name: COPS4 Antibody
SKU: CSB-PA880098ESR2HU_C90
Availability: BackOrder

CSB-PA880098ESR2HU

ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman

TargetCOPS4

Overview

Supplier
Cusabio
Product Name
COPS4 Antibody
Delivery Days Customer
20
Applications
Western Blot, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID51138
Target name
COPS4
Target description
COP9 signalosome subunit 4
Target synonyms
COP9 constitutive photomorphogenic homolog subunit 4; COP9 constitutive photomorphogenic-like protein subunit 4; COP9 signalosome complex subunit 4; CSN4; JAB1-containing signalosome subunit 4; SGN4; signalosome subunit 4; testis tissue sperm-binding protein Li 42a
Host
Rabbit
Isotype
IgG
Protein IDQ9BT78
Protein Name
COP9 signalosome complex subunit 4
Scientific Description
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. Also involved in the deneddylation of non-cullin subunits such as STON2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1, IRF8/ICSBP and SNAPIN, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

COPS4 Antibody

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