Western blot All lanes: COP9 signalosome complex subunit 7a antibody at 4ug/ml Lane 1: Rat heart tissue Lane 2: Rat brain tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 30 kDa Observed band size: 30 kDa
Western blot All lanes: COP9 signalosome complex subunit 7a antibody at 4ug/ml Lane 1: Rat heart tissue Lane 2: Rat brain tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 30 kDa Observed band size: 30 kDa
COPS7A Antibody
CSB-PA880068ESR1HU
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCOPS7A
Overview
- SupplierCusabio
- Product NameCOPS7A Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID50813
- Target nameCOPS7A
- Target descriptionCOP9 signalosome subunit 7A
- Target synonymsCOP9 complex subunit 7a; COP9 constitutive photomorphogenic homolog subunit 7A; COP9 signalosome complex subunit 7a; CSN7; CSN7A; dermal papilla-derived protein 10; JAB1-containing signalosome subunit 7a; SGN7a
- HostRabbit
- IsotypeIgG
- Protein IDQ9UBW8
- Protein NameCOP9 signalosome complex subunit 7a
- Scientific DescriptionComponent of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203