Western Blot Positive WB detected in: Mouse brain tissue, Mouse stomach tissue All lanes: COPS7B antibody at 3microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 30, 19, 31 kDa Observed band size: 30 kDa
Western Blot Positive WB detected in: Mouse brain tissue, Mouse stomach tissue All lanes: COPS7B antibody at 3microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 30, 19, 31 kDa Observed band size: 30 kDa
COPS7B Antibody
CSB-PA872526LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCOPS7B
Overview
- SupplierCusabio
- Product NameCOPS7B Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID64708
- Target nameCOPS7B
- Target descriptionCOP9 signalosome subunit 7B
- Target synonymsCOP9 constitutive photomorphogenic homolog subunit 7B; COP9 signalosome complex subunit 7b; CSN7B; JAB1-containing signalosome subunit 7b; SGN7b; signalosome subunit 7b
- HostRabbit
- IsotypeIgG
- Protein IDQ9H9Q2
- Protein NameCOP9 signalosome complex subunit 7b
- Scientific DescriptionComponent of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203