COQ3 antibody

GeneTex

COQ3 antibody

9

WB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

Unconjugated

COQ3

coenzyme Q3, methyltransferase

DHHBMT, DHHBMTASE, UG0215E05, bA9819.1, ubiquinone biosynthesis O-methyltransferase, mitochondrial, 2-polyprenyl-6-hydroxyphenol methylase, 2-polyprenyl-6-hydroxyphenyl methylase, 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase, 3-demethylubiquinol 3-O-methyltransferase, 3-demethylubiquinone 3-O-methyltransferase, 3-demethylubiquinone-10 3-methyltransferase, DHHB methyltransferase, DHHB-MTase, coenzyme Q3 homolog, methyltransferase, dihydroxyhexaprenylbenzoate methyltransferase, hexaprenyldihydroxybenzoate methyltransferase, mitochondrial, methyltransferase COQ3, polyprenyldihydroxybenzoate methyltransferase

Rabbit

IgG

Ubiquinone biosynthesis O-methyltransferase, mitochondrial

Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.[supplied by OMIM, Mar 2008]

-20°C or -80°C,2°C to 8°C

12352203