
Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA896913ESR1HU at dilution of 1:100
CORIN Antibody
CSB-PA896913ESR1HU
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
TargetCORIN
Overview
- SupplierCusabio
- Product NameCORIN Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID10699
- Target nameCORIN
- Target descriptioncorin, serine peptidase
- Target synonymsATC2; atrial natriuretic peptide-converting enzyme; CRN; heart-specific serine proteinase ATC2; Lrp4; PEE5; pro-ANP-convertase; pro-ANP-converting enzyme; TMPRSS10; transmembrane protease serine 10
- HostRabbit
- IsotypeIgG
- Protein IDQ9Y5Q5
- Protein NameAtrial natriuretic peptide-converting enzyme
- Scientific DescriptionSerine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203